解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The aim of a case-control design is to make a measurement of the highest possible accuracy, reducing to a minimum the possible selection, information and confusion biases. The design, methods and procedures of a multicentric study carried out in 14 hospitals from 4 autonomous communities in Spain are discussed. Overal...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1989-05-06 00:00:00
abstract::Epstein-Barr virus (EBV) infection is ubiquitous and may result in multiple and widely different clinical features; the most common of these is infectious mononucleosis (IM). Recently, a group of patients has been included in the chronic EBV infection syndrome (EBVIS), with a sustained nonspecific syndrome consisting ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-04-29 00:00:00
abstract::We have evaluated the close contacts of 191 patients diagnosed of tuberculosis in our center between 1984 and 1987. The overall number of evaluated contacts was 666, and the mean number of contacts for each index case was 3.7. In 55% of the evaluated population PPD reaction was positive, and their mean age was 33.3 ye...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-04-22 00:00:00
abstract::Primary hyperparathyroidism (PH) is now considered a common condition. Its frequency and the deleterious long-term effects of hypercalcemia make a correct diagnosis mandatory. We attempted to evaluate the usefulness of the indexes of parathyroid function and hormone measurements more commonly used in the diagnosis of ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-04-08 00:00:00
abstract::Dissecting aneurysm of the aorta keeps on being nowadays a diagnostic problem, although it is a well known entity. Dissecting aneurysms may be classified into type A, dissection involving the ascending aorta, and type B, dissection involving descending aorta. The frequency of neurologic manifestations oscillates from ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::Highly malignant non-Hodgkin lymphomas (HM-NHL) may sometimes develop clinical features simulating an epithelial carcinoma with metastatic dissemination. Conventional histopathological study may be insufficient to differentiate between both conditions. Two patients with HM-NHL are reported with a rapid general deterio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-03-11 00:00:00
abstract::We have evaluated 100 biopsies of temporal artery carried out in the Hospital La Paz from 1972 to 1986. On the basis of the histological result and the final diagnosis we divided the patients in five groups: I, temporal arteritis/polymyalgia rheumatica with positive biopsy, 11 cases; II, temporal arteritis without pol...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-01-28 00:00:00
abstract::The advances in contraceptive and sterilization methods likely to be available within the next few years will probably consist of improvements of existing methods rather than revolutionary new techniques. Among female vaginal methods, vaginal sponges incorporating spermicides have been constructed of collagen or poly...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1985-11-02 00:00:00
abstract::The authors report a patient who developed a mononucleotic syndrome after 2 months treatment with diphenylhydantoin. The clinical and biological criteria needed to establish the diagnosis of pseudomononucleosis are listed, while other possible causes described in the literature have been excluded. Complications which ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-10-10 00:00:00
abstract::The electrocardiogram as a diagnostic aid in acute myocardial infarction of the right ventricle (AMI-RV) was studied prospectively in a group of 66 patients in our coronary unit. Diagnosis was AMI in all cases, divided into 29 (44%) with posterior-descending and 35 (53%) with anterior location. Electrocardiography was...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-09-25 00:00:00
abstract::Accumulation of pus in the perinephritic cavity often gives rise to doubtful clinical manifestations, which hinder and delay prompt diagnosis of this severe process. The clinical, biological, radiological and therapeutic characteristics of 50 cases are reviewed; all were confirmed by either surgery or necropsy. The mo...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-07-15 00:00:00
abstract::Due to a combination of ingested ethanol and inhaled trichloroethylene (Tri) a 28 year old man developed toxic hepatitis and acute oliguric renal failure, both of which had a favorable evolution. Tri has been described as a cause of hepatic disfunction and acute renal failure due to acute tubular necrosis, although so...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-06-25 00:00:00
abstract::A case of rapidly progressive glomerular disease with 100% of epithelial crescents completely enveloping each glomerulus, prolonged anuria and renal failure requiring dialysis. There were no indications of either streptococcal etiology or systemic disease. Improvement in renal function in response to plasmapheresis an...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-06-10 00:00:00
abstract::Out of 110 cases of fever of unknown origin (FUO) that met Petersdorf and Beeson's criteria 15 patients were selected because of prolonged FUO with more than six months elapsed between admission and the final diagnosis. In this group of chronic FUO an etiological diagnosis was reached in 11 cases, distributed as follo...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-05-10 00:00:00
abstract::The serum levels of cholesterol bound to high density lipoproteins (HDL-C) were determined by the heparin-manganese chloride precipitation method in 306 subjects, 182 male with ages ranging from 11 to 81 years, and 124 female with ages ranging from 7 to 78 years. Twenty six subjects belonged to a lacto-vegetarian comm...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-03-25 00:00:00
abstract::The authors study the usefulness of the measurement of the negative area of P in V1 (Morris' index) in patients with acute myocardial infarction. The study was carried out prospectively in 70 patients, 31 of them having a Swan-Ganz catheter inserted permitting simultaneous hemodynamic and electrocardiographic measurem...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-03-10 00:00:00
abstract::A prospective clinical and electrophysiologic study was performed in 50 alcoholic patients in order to assess the incidence and clinical manifestations of alcoholic polyneuropathy, the value of the electrophysiologic parameters studied, and the influence of liver disease on the appearance of neuropathy. The proposed c...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-03-10 00:00:00
abstract::The existence of an increasing number of apparently healthy carriers of the HBsAg demands a specific assisting attitude which must be highly reliable without increasing health care expenses. With that purpose, 129 asymptomatic carriers without prior history of jaundice and/or alcohol abuse were studied. The following ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-02-25 00:00:00
abstract::Fosfosal or 2-phosphonoxybenzoic acid is a new analgesic drug, whose analgesic activity and side effects have been determined in a double blind clinical study in comparison with placebo. The study has been done with 60 outpatients, of both sexes, which suffered musculoskeletal and arthritic pains. Patients were treate...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1981-01-10 00:00:00
abstract::Cephotaxime (HR 756) is a new cephalosporin antibiotic of wide spectrum and extraordinary activity, suitable for parenteral administration. It is highly resistant to the beta-lactamases of Gram negative bacilli, being thus especially active against microorganisms such as indole-positive Proteus, Serratia marcencens, a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-11-25 00:00:00
abstract::A 75 year-old male presented with hyperkalemia unexplained by a moderate renal insufficiency, low basal levels of aldosterone and renin with a subnormal response to walking and saline depletion, and normal glucocorticoid function. The hyperkalemia was corrected by fluorocortisone administration. The concept of hypoald...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-11-10 00:00:00
abstract::The incidence and clinical course of urinary tract infections in postmenopausal diabetic patients in comparison to non-diabetic women have been evaluated. All cases with former history of urinary instrumentation or underlying conditions favoring urinary infections were rejected. Urinary tract infection was present in ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-10-10 00:00:00
abstract::During a period of 29 months positive hemocultures to Streptococcus agalactiae corresponding to eight adult patients have been observed. These bacteria were apparently responsible for the clinical picture in five patients. In other two patients S. agalactiae appeared in the course of a sepsis caused by other germ. The...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-09-25 00:00:00
abstract::The characteristics of previous potentials of somatosensory evoked potential in 12 patients with lesions of the brain-stem and in 24 normal individuals have been studied. Lesions of the brain-stem were confirmed by means of computerized axial tomography, arteriography or necropsy. According to data reported by other a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-09-25 00:00:00
abstract::A group of 39 patients has been divided in three categories according to their plasmatic renine activity and the correlation of the hipotensive answer to the Timolol Maleate (betadrenergic blocking). The control is more favourable in the normorreninemic than in the hiporreninemic patients and, paradoxically, even more...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-09-10 00:00:00
abstract::Associated coronary atherosclerosis in patients with rheumatic valvular heart disease is an important finding under prognostic and therapeutic viewpoints. Selective coronary angiography was carried out in 300 patients with rheumatic valvular disease (157 cases with associated mitral and aortic lesions; 57 cases with a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-07-15 00:00:00
abstract::Pseudomonas infections continue to be an important problem in the hospital environment. Serious infections are always invariably associated with severe underlying conditions or with diminished host resistance. The increasingly resistance of strains and hospital epidemics favour the organism prevalence. During 1978, Ps...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-07-15 00:00:00
abstract::Familial hypophosphoremic rickets, although exceptional, is a frequent form of presentation in communities where nutritional rachitism has been eradicated. Hypophosphoremia is the biochemical defect which led to an insuffieient osseous mineralization. The real pathogenic mechanism of the disease is still unknown. Two ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-04-10 00:00:00
abstract::The familial periodic hypokalemic paralysis is an infrequent disease characterized by paralytic attacks of sudden appearance affecting the muscles of the trunk and limbs. There is a marked hypokalemia during the paralytic episodes of the disease, and a family history in 80 percent of the cases. The differential diagno...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-03-10 00:00:00
abstract::The authors report a case of hepatorenal polycystic disease discovered in the course of a routine physical examination. The patient was asymptomatic and the progression of the disease was extremely low. The existence of the disorder, however, was confirmed in the autopsy. Although hepatorenal polycystic disease is a r...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-02-10 00:00:00
abstract::Since uricosuria is an essential compensative factor in hyperuricemia, multiple factors exist which can influence on the uric acid excretion in the tubules. Normally, 90% of the uric acid filtered by the glomerulus is reabsorbed, and its active tubular secretion forms the greater part of the uric acid present in the u...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-02-10 00:00:00
abstract::This article presents six cases of hemolytic-uremic syndrome, defined as the combination of acute renal insufficiency, microangiopathic hemolytic anemia, and thrombocytopenia, in six adult patients, two men and four women, between 20 and 52 years old. Three of the cases were considered idiopathic, two secondary to the...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1980-01-10 00:00:00
abstract::The hemophagocytosis or the process of ingestion of blood cells by phagocytes and macrophages of the mononuclear phagocytic system (MFS), is a phenomenon that rarely could be observed in the morphological examination of the bone marrow aspirate. Occasionally it is present in certain pathologic conditions such as, mali...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-12-15 00:00:00
abstract::The authors present a study of 50 patients with adenocarcinomas of the colon and rectum, patients with gastric adenocarcinomas, and 30 healthy individuals as a control group. In all subjects the following parameters were determined: total number of lymphocytes in the peripheral blood, T lymphocytes, T-active lymphocyt...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-12-15 00:00:00
abstract::The coexistence of organ-specific and nonorgan-specific autoimmune diseases is an interesting phenomenon. A 52-year-old woman was admitted with fever, general discomfort, polyarthritis, and Raynaud's phenomenon. Physical examination revealed a goiter of stony consistency, hardening, paleness, and atrophy of the skin o...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-11-10 00:00:00
abstract::A case of primary amyloidosis in which multinucleated giant cells occurred in relation to amyloid deposits in the renal-glomerulus and in multiple other organs is reported. The ubiquity of multinucleated giant cells distinguishes the present case from those previously described in the literature. It is felt that the f...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-11-10 00:00:00
abstract::The association of nephrotic syndrome and renal vein thrombosis has been increasingly reported in the literature due to the use of modern complementary explorative techniques. The incidence of renal vein thrombosis in the nephrotic syndrome varies according to the different authors. The pathogenesis of this associatio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-10-10 00:00:00
abstract::A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-08-15 00:00:00
abstract::The handling of patients with cerebral ischemia is reviewed, taking into consideration recent concepts regarding etiopathogenesis along with new diagnostic and therapeutic methods. A particularly important new diagnostic method is computerized axial tomography. The subject is divided into four sections in order to pre...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-05-25 00:00:00
abstract::Bile acids play a fundamental role in the degradation and absorption of intestinal lipids. The primary ones are cholic acid and chenodeoxycholic acid which are synthesized from cholesterol in the liver and conjugate with taurine and glycine amino acids. The secondary bile acids are derived from the primary ones by the...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-04-10 00:00:00